radiation therapy is considered as one of the main methods in cancer treatment. in this method, determination of exact location and geometric properties of tumor is necessary for treatment planning that leads to increased accuracy and output of treatment and reduction of healthy tissue dose. for this purpose, the aim of the present study has been physiological transmission of gallium as a pharm...

Accuracy of the radiotherapy requires some routine quality control and dosimetry calculations, which would be done by radiotherapy physicists. Due to the increasing use of computers and simulation software in medical science, as well as trends indicating its continued growth, this study aims to develop a new smart-phone application to perform common radiotherapy-related calculations. Computatio...

Introduction: Successful radiotherapy requires the precise application of a radiation dose to cancerous tissue, which can be achieved by the design of proper treatment methods by radiotherapy physicists. Tasks performed by radiotherapy physicists include verifying the accuracy of dose calculations, correct treatment planning and the proper functioning of accelerators. They are...

The outcomes for patients with esophageal cancer (EC) underwent standard-dose radical radiotherapy were still disappointing. This phase II study investigated the feasibility, safety and efficacy of radiation dose escalation using simultaneous modulated accelerated radiotherapy (SMART) combined with chemotherapy in 60 EC patients. Radiotherapy consisted of 66Gy at 2.2 Gy/fraction to the gross tu...

BACKGROUND The SMART trial is a UK-based, multicentre RCT comparing prophylactic radiotherapy and symptom-based (deferred) radiotherapy in 203 patients with Malignant Pleural Mesothelioma who had undergone large bore pleural interventions. Using costs and quality of life data collected alongside the clinical trial, we will estimate the cost-effectiveness of prophylactic radiotherapy compared to...

This study aimed to evaluate the efficacy, toxicity and tolerability of simultaneous modulated accelerated radiation therapy (SMART)-intensity modulated radiotherapy (IMRT) plus cisplatin and 5-fluorouracil (5-FU) chemotherapy for patients with advanced nasopharyngeal cancer (NPC). Forty-five patients with stage II-IV NPC, determined by the American Joint Committee on Cancer system, were treate...

OBJECTIVES To evaluate the feasibility and efficacy of simultaneous accelerated radiation therapy (SMART) and concurrent weekly paclitaxel in the treatment of locally advanced nasopharyngeal carcinoma. METHODS Forty- one patients with pathologically confirmed nasopharyngeal carcinoma were treated by SMART with concurrent weekly paclitaxel. Daily fraction doses of 2.5 Gy and 2.0 Gy were prescr...